Why people ask it
Because science has replaced supernatural explanations for many things, and it feels like the trend continues all the way down.
Short answer
No. Science studies the measurable physical world. Whether reality extends beyond the physical is not a measurable question, so no experiment could settle it in either direction.
Deeper answer
This is a category question, not a scientific one. Science works by observation, measurement and prediction of physical phenomena. That method is spectacularly reliable inside its domain, and Christians should say so plainly rather than hedging.
But the method has a boundary built into it. Asking whether anything exists beyond the measurable is not a question the instruments reach. That is not a defect; a thermometer that cannot measure justice is not broken.
What people usually mean by "science disproved God" is that science explained mechanisms once attributed to divine action. That is true and it is real progress. It is also a claim about the history of explanation, not a finding about whether God exists.
Common mistake
God-of-the-gaps reasoning — placing God in whatever science has not yet explained. That territory shrinks every decade.
Conversation-ready response
""What experiment do you think could settle it either way? I am genuinely asking, because I cannot design one — and that is the point I want to make.""
Source notes coming soon.